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Yohimbe 

Yohimbe
(Pausinystalia yohimbe)

General Description:  Yohimbe is a West African tree native to Congo, Cameroon, and Gabon.  The main ingredient is Yohimbine, is an alkaloid found in the roots. .   

Part Used:  Roots and bark

Uses:     

  erectile dysfunction (conflicting studies)

   impotence

  orthostatic hypotension

 clonidine overdose 

Action:  Yohimbine  is the alkaloid that is chemically active and responsible for the effects of yohimbe.  It is an alpha-2 adrenergic receptor.

CNS – stimulant effect

Periphery- releases norepinephrine, to increase penile blood flow

Dosage:  15-20 mg. per day

Precautions/Adverse Reactions:    In clinical trials, it did not effect the sexual performance of sexually functioning men. It does have a high-risk–to benefit ratio because of side effects: nervousness, irritability, dizziness, headache, sweating, hypertension, tachycardia, psychoses, hallucinations, and one report of renal failure, and a lupus-like syndrome.

          Interactions with other Drugs:  OTC stimulants (caffeine, phenylephedrine, phenylpropanolamine), SSRI's, Tricyclic antidepressants, and foods containing tyramine.

Contraindications:  Renal disease,  hepatic disease, psychiatric disorders, and uncontrolled hypertension.

Nursing Considerations: 

   Yohimbe can counteract the benefits of antihypertensive meds.

  Monitor for CNS and cardiac effects.

    Do  not use with Clonidine.   It competes with the receptors and can cause a hypertensive  crisis.   

   Yohimbe can counteract mood-modifying meds such as antidepressants.  Warn patients not to use concurrently. 

   Due to a weak MAOI activity, do not eat tyramine containing foods, or decongestants or stimulants.

   Avoid caffeine.                  

  Yohimbine is used widely despite that it does not have FDA  approval. It has been on their unsafe list since 1977                  

   Standard dose is 5.4 mg only by prescription.         

   Yohimbe is a dietary supplement, often in combination with other herbs.            

   Recommended to be used under the care of a physician.

(References)

        

Aloe ] Bilberry ] Black Cohash ] Chamomile ] Chaste Berry Tree ] Dong Quai ] Echinacea ] Evening Primrose Oil ] Feverfew ] Garlic ] Ginger ] Ginkgo ] Ginseng ] Guarana ] Hawthorn ] Horse Chestnut ] Kava-Kava ] Ma Huang ] Milk Thistle ] Nettle ] St. John's Wort ] Saw Palmetto ] Tea Tree Oil ] Valerian ] [ Yohimbe ]